Saturday 28 November 2015

FDA says “no” to aspirin… Will you still use it?

Figure 1: Aspirin. From Aspirin by M. Perry, 2013, https://www.flickr.com/photos/curtisperry/8346000354/in/photolist-dHvr8Q-oEnpWV-mWPUg-gau7ip-qnEQXH-g1aTPt-dYHcqy-x2rue-6YXu6R-9dxqQE-6Qxjaz-aHrBs8-gQ2rdR-5a6hQC-dYcvqv-kzULKm-fDCH5K-6oqFc-5a6hqG-5R8s7Z-g7EG5G-g7EmMA-9mqWkR-iV96YE-6E4REU-jjhka-gFdGsP-7PEoDk-dYidgS-fYd7yU-ggTcmF-2mboMn-gc8Brz-dKawU2-fDVjHL-7BCmFu-oA8S5o-fz3GxD-g7Eewx-g7E6rV-bhhkya-pptbfK-5a1LF8-fAeLZ6-gMAc1A-iRcfrY-fAu7iw-nz2DDa-7DLioc-fLcaXf

In 2014, the FDA, Food and Drug Administration, issued a message to consumers stating that the evidence does not support the general use of aspirin as a primary prevention for heart attacks and strokes.” This announcement came shortly after the FDA rejected Bayer’s request to put this information on their labels for aspirin (Neale, 2014). This news has caused individuals to question the safety and benefits of aspirin. The American Heart Association, U.S Preventive Service Task Force, and most cardiologists still recommend aspirin for primary prevention of heart attacks or strokes (Neale, 2014).

To me, this is strange, as aspirin has been around for a long time and doctors have used it for decades. Aspirin has been known for its four important uses: to relieve pain, reduce inflammation, reduce fever, and prevent the formation of blood clots (Schlager et al., 2006). When taking aspirin, it prevents cells called platelets from clumping together and blocking arteries which can cause blood clots and lead to heart attacks (Schlager et al., 2006).

But after saying that, it is important to be aware of the side effects from taking aspirin. When aspirin is taken in vast amounts and over a very short time period it could cause gastrointestinal bleeding (Mayo Clinic, 2015)., renal failure (National Kidney Foundation, 2009), platelet dysfunction (Kuter, 2014) and Reye’s syndrome (Schlager et al., 2006) in children.

It has been supported that aspirin is recommended for people who are at risk or who have had a heart attack or stroke. For those you do not fall into those categories and younger persons, aspirin can be used for its anti-inflammatory, pain reliever, and fever reducer properties.

References:

Kuter, D.J. (2014). Platelet Dysfunction. In Merck Manuals (September 2014 text rev.). Retrieved from http://www.merckmanuals.com/professional/hematology-and-oncology/thrombocytopenia-and-platelet-dysfunction/acquired-platelet-dysfunction


National Kidney Foundation. (2009). Pain Medicines (Analgesics). Retrieved November 17, 2015, from https://www.kidney.org/atoz/content/painMeds_Analgesics

Neale, T. (2014, May). Aspirin: FDA Says ‘No’ Others Say ‘Yes’. MedPage Today. Retrieved from http://www.medpagetoday.com/Cardiology/Prevention/45634


Schlager, E. N., Weisblatt, J., & Newton, D. E. (2006). Acetylsalicylic Acid., Chemical Compounds (pp. 31-35). Detroit: UXL

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